511 TOTAL PARENTERAL NUTRITION-RELATED CHOLESTASIS IN INFANTS
نویسندگان
چکیده
منابع مشابه
Total parenteral nutrition in surgical infants.
Introduction The newborn infant is in a 'critical epoch' of development. Nutritional deprivation may adversely affect not only the infant as a whole but also individual organs, notably the brain, leading to stunted physical and intellectual development [l]. In the surgical infant malnutrition is associated with increased morbidity and mortality; therefore, it is important that nutritional integ...
متن کاملParenteral nutrition associated cholestasis
Parenteral nutrition (PN) is life saving for many preterm infants and other neonates with severe illness, but prolonged use of PN can lead to intrahepatic cholestasis, referred to as parenteral nutrition–associated cholestasis (PNAC). It is defined as direct bilirubin greater than 2.0 mg/dL persistent for at least 2 consecutive tests duringthe administration of PN, not associated with other kno...
متن کاملTotal Parenteral Nutrition – Associated Cholestasis (TPNAC) in Newborns
Pediatrics Gastroenterologist & Master in Clinical Nutrition, Chief of Pediatrics Gastroenterology, Hepatology and Nutrition Department, Clínica del Niño PREVIANDES & Professor of Pediatric Gastroenterology & Pediatric Department Universidad El Bosque, Master in Clinical Nutrition and Professor of Pediatric Gastroenterology & Pediatric Department Universidad El Bosque, Pediatrician visitors Cor...
متن کاملEffect of S-adenosylmethionine on total parenteral nutrition-associated cholestasis
Methods: Twenty-four newborn rabbits were randomly divided into 3 groups: normal control group receiving breast milk, TPN group receiving TPN at a dose of 200 kcal/kg per day, and SAMe group receiving TPN plus SAMe at an intravenous dose of 100 mg/kg per day. Blood and liver samples were collected one week later. The levels of serum bile acid, alanine aminotransferase (ALT), alkaline phosphatas...
متن کاملAggressive nutrition in extremely low birth weight infants: impact on parenteral nutrition associated cholestasis and growth
BACKGROUND Parenteral nutrition associated cholestasis (PNAC) is a frequently observed pathology in extremely low birth weight (ELBW) infants. Its pathogenesis is determined by the composition and duration of parenteral nutrition (PN) as well as the tolerance of enteral feeds (EF). "Aggressive" nutrition is increasingly used in ELBW infants to improve postnatal growth. Little is known about the...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198504000-00541